Journal
EUKARYOTIC CELL
Volume 6, Issue 2, Pages 346-350Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/EC.00336-06
Keywords
-
Categories
Funding
- NHLBI NIH HHS [R01HL0636] Funding Source: Medline
- NIAID NIH HHS [R01 AI059201, 1R01AI059201] Funding Source: Medline
Ask authors/readers for more resources
Many single-celled eukaryotes produce prostaglandin-like molecules, but these have not been absolutely verified by mass spectrometry. We have isolated, and identified by liquid chromatography-tandem mass spectrometry, authentic prostaglandin E-2 from Cryptococcus neoformans. Cyclooxygenase inhibitors did not inhibit prostaglandin synthesis, and the cryptococcal genome lacks a cyclooxygenase homolog. Thus, novel enzymes must exist.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available