Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 73, Issue 3, Pages 997-1001Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.00865-06
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In alkaline conditions, Listeria monocytogenes cells develop higher proportions of branched-chain fatty acids (FAs), including more anteiso forms. In acid conditions, the opposite occurs. Reduced growth of pH-sensitive mutants at adverse pH (5.0/9.0) was alleviated by the addition of 2 -methylbutyrate (an anteiso-FA precursor), suggesting that anteiso-FAs are important in adaptation to adverse pH. The balance between anteiso- and iso-FAs may be more important than changes in the amounts and/or degrees of saturation of FAs in pH adaptation.
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