Journal
HAEMATOLOGICA
Volume 92, Issue 2, Pages 283-284Publisher
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.10667
Keywords
immune thrombocytopenia; platelet autoantibody specificity; intravenous immunoglobulin
Categories
Funding
- Gundersen Lutheran Center for Cancer and Blood Disorders
- Gundersen Lutheran Medical Foundation
Ask authors/readers for more resources
We retrospectively investigated the association between platelet autoantibody specificity and response to intravenous immunoglobulin G (IVIG) in 17 patients with immune thrombocytopenia (ITP). Platelet-associated antibodies against glycoprotein (GP) IIb/IIIa, GPIb/IX, and GPIa/IIa were detected in 13, 10, and 8 patients, respectively. A response occurred in 7 of 7 patients without anti-GPIb/IX, but in only 3 of 10 patients with anti-GPIb/IX (p<0.01). There was no difference in the response rates in patients with or without anti-GPIIb/IIIa or anti-GPIa/IIa. We conclude that ITP patients with anti-GPIb/IX may be less responsive to IVIG.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available