Journal
CHEMMEDCHEM
Volume 2, Issue 2, Pages 175-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cmdc.200600250
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Funding
- Biotechnology and Biological Sciences Research Council Funding Source: Medline
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An approach combining thiol based dynamic chemistry and MS was used to explore the SAR of a metallo-beta-lactamase. Analogues of preferentially binding disulfides were synthesized and shown to be potent inhibitors.
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