Journal
ORGANIC LETTERS
Volume 9, Issue 3, Pages 409-412Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol062766v
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An efficient and one-step synthesis of 3-aminoindolizines or benz[e]indolizines from the reactions of propargyl amines or amides with heteroaryl bromides was developed. This methodology is realized by a tandem reaction using Pd/Cu catalysts, which could catalyze coupling and cycloisomerization reactions in the same vessel.
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