4.8 Article

Stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin

Journal

ORGANIC LETTERS
Volume 9, Issue 3, Pages 533-536

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0629869

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Funding

  1. NIGMS NIH HHS [R01 GM038436, R01 GM038436-22, GM 38436] Funding Source: Medline

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A stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin has been accomplished via a highly diastereoselective double allylboration reaction of 6-8 and an iodonium ion promoted urethane cyclization for the installation of the C(15) alkoxy function in 3.

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