Journal
HAEMATOLOGICA
Volume 92, Issue 2, Pages 279-280Publisher
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.10454
Keywords
newly diagnosed multiple myeloma; coagulation abnormalities; vWF; factor VIII; antiphospholipid antibodies; protein S
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Prothrombotic coagulation abnormalities were analyzed in patients with untreated multiple myeloma. Increases in factor VIII, in von Willebrand factor and a decrease in protein S were observed and these changes were strongly associated with disease stage. No difference in baseline coagulation parameters was found between patients with and without subsequent venous thromboembolism.
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