Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 45, Issue 2, Pages 627-630Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00816-06
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Using in vivo samples from treatment failure malaria cases, we demonstrate the high sensitivity of the parasite lactase dehydrogenase (pLDH)-based OptiMAL rapid diagnostic test in the detection of P. falciparum gametocytes. This high sensitivity limits the use of pLDH-based tests in the monitoring of treatment outcomes in circumstances where gametocytemia is common.
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