Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 57, Issue 2, Pages 297-307Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.21115
Keywords
selective excitation; outer volume suppression; rFOV spiral imaging; distortion reduction; dynamic time series; fetal MRI; fMRI
Funding
- NCI NIH HHS [T32 CA09695, R33 CA88205] Funding Source: Medline
- NCRR NIH HHS [P41 RR09784] Funding Source: Medline
- NIBIB NIH HHS [1R01EB002771] Funding Source: Medline
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A restricted field of view (rFOV) approach for imaging a dynamic time series of volumes of limited spatial extent within a larger subject is described. The shorter readout with rFOV-MRI can be exploited to either limit image artifacts or increase spatial resolution. To accomplish rFOV imaging of a multislice volume for a dynamic series, an outer volume suppression (OVS) preparation that saturates signal external to a cylinder through the subject is followed by slice-selective excitation and a spiral readout. The pass- and stopband efficiencies of the OVS in an agar gel phantom were 97% (+/- 1.5%) and 3% (+/- 1%), respectively. Profiles of the temporal signal-to-noise ratio (SNR) were measured in a phantom and an adult brain. The rFOV sequence reduced distortions from off-resonance signal and T-2*-induced blurring compared to a conventional sequence. Sequence utility is demonstrated for high-resolution rFOV functional MRI (fMRI) in the visual cortex. The rFOV sequence may prove to be useful for other multislice dynamic and high-resolution imaging applications. Magn Reson Med 57:297-307, 2007. (c) 2007 Wiley-Liss, Inc.
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