Journal
HAEMATOLOGICA
Volume 92, Issue 2, Pages 264-266Publisher
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.10356
Keywords
T-ALL; thymocytes; BM stroma; IL-7; survival; proliferation
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Funding
- Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR)
- Consiglio Nazionale delle Ricerche (CNR)
- Fondazione Cariverona, Verona, Italy
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We explored the role of interleukin-7 (IL-7) in the bone marrow (BM) stroma-mediated survival of primary T-cell acute lymphoblastic leukemia (T-ALL) cells and normal thymocytes. We present evidence that IL-7 has a major role in the enhanced survival mediated by BM stroma both in T-ALL cells and thymocytes.
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