Journal
FEMS MICROBIOLOGY LETTERS
Volume 267, Issue 2, Pages 131-144Publisher
OXFORD UNIV PRESS
DOI: 10.1111/j.1574-6968.2006.00573.x
Keywords
crystalline surface layers; S-layers; S-layer fusion proteins; self-assembly; bottom-up strategy; nanobiotechnology
Categories
Funding
- Austrian Science Fund FWF [P 20256] Funding Source: Medline
Ask authors/readers for more resources
Crystalline bacterial cell surface layers (S-layers) have been identified in a great number of different species of bacteria and represent an almost universal feature of archaea. Isolated native S-layer proteins and S-layer fusion proteins incorporating functional sequences self-assemble into monomolecular crystalline arrays in suspension, on a great variety of solid substrates and on various lipid structures including planar membranes and liposomes. S-layers have proven to be particularly suited as building blocks and patterning elements in a biomolecular construction kit involving all major classes of biological molecules (proteins, lipids, glycans, nucleic acids and combinations of them) enabling innovative approaches for the controlled 'bottom-up' assembly of functional supramolecular structures and devices. Here, we review the basic principles of S-layer proteins and the application potential of S-layers in nanobiotechnology and biomimetics including life and nonlife sciences.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available