4.5 Article

Chemico-enzymatic synthesis of a new fluorescent-labeled DNA by PCR with a thymidine nucleotide analogue bearing an acridone derivative

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 17, Issue 3, Pages 776-779

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.10.072

Keywords

acridone; fluorescent-labeled DNA; PCR; DNA probe

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Triphosphate of a thymidine analogue bearing acridone was prepared and incorporated as a substrate for P using KOD Dash DNA polymerase forming a new fluorescent-labeled DNA that is useful as a DNA probe. (c) 2006 Elsevier Ltd. All rights reserved.

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