4.4 Article

Expression of a liver-specific function by a hepatoblastoma cell line cocultured with three-dimensional endothelialized tubes in collagen gels

Journal

JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 103, Issue 2, Pages 200-202

Publisher

SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1263/jbb.103.200

Keywords

endothelialized tube; three-dimensional configuration; Hep G2; collagen gel; tissue engineering

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A human hepatoblastoma cell line, Hep G2, showed albumin production activity, a hepatic function, when cocultured with three-dimensional endothelialized tubes in collagen gels. The albumin production rate of the collagen-based liver-like constructs increased with increasing length of the endothelialized tube in the construct.

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