Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 53, Issue 28, Pages 7272-7276Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201403774
Keywords
allenes; aminals; C-N activation; diamines; palladium
Categories
Funding
- Chinese Academy of Sciences
- National Natural Science Foundation of China [21222203, 21172226, 21133011]
Ask authors/readers for more resources
A new and atom-economic palladium-catalyzed aminomethylamination of allenes with aminals by C-N bond activation is described. This direct and operationally simple method provides a fundamentally novel approach for the synthesis of 1,3-diamines. Mechanistic studies suggest that a unique cationic pi-allylpalladium complex containing an aminomethyl moiety is generated as a key intermediate through the carbopalladation of the allene with a cyclometalated palladium-alkyl species.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available