Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 7, Pages 2199-2203Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201408630
Keywords
C-H activation; heterocycles; oxidation; radicals; silver
Categories
Funding
- 973 Program [2011CB932404, 2011CBA00501]
- NSFC [21332001, 21431008, 21301173]
- CAS/SAFEA International Partnership Program for Creative Research Teams
Ask authors/readers for more resources
A long-standing challenge in Minisci reactions is achieving the arylation of heteroarenes by oxidative decarboxylation of aromatic carboxylic acids. To address this challenge, the silver-catalyzed intermolecular Minisci reaction of aromatic carboxylic acids was developed. With an inexpensive silver salt as a catalyst, this new reaction enables a variety of aromatic carboxylic acids to undergo decarboxylative coupling with electron-deficient arenes or heteroarenes regardless of the position of the substituents on the aromatic carboxylic acid, thus eliminating the need for ortho-substituted aromatic carboxylic acids, which were a limitation of previously reported methods.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available