Journal
STROKE
Volume 38, Issue 2, Pages 817-826Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/01.STR.0000247888.25985.62
Keywords
clinical trials; neural stem/progenitor cells; stroke; transplantation parameters
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Funding
- NINDS NIH HHS [2P01 NS37520, 2R01 NS27292] Funding Source: Medline
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No treatment currently exists to restore lost neurological function after stroke. A growing number of studies highlight the potential of stem cell transplantation as a novel therapeutic approach for stroke. In this review we summarize these studies, discuss potential mechanisms of action of the transplanted cells, and emphasize the need to determine parameters that are critical for transplantation success. (Stroke. 2007;38[part 2]:817-826.)
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