Journal
CURRENT OPINION IN NEUROBIOLOGY
Volume 17, Issue 1, Pages 120-127Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2006.09.004
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- NINDS NIH HHS [NS25713] Funding Source: Medline
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Chondroitin sulfate proteoglycans are the principal inhibitory component of glial scars, which form after damage to the adult central nervous system and act as a barrier to regenerating axons. Recent findings have furthered our understanding of the mechanisms that result in a failure of regeneration after spinal cord injury and suggest that a multipartite approach will be required to facilitate long-distance regeneration and functional recovery.
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