Journal
TETRAHEDRON LETTERS
Volume 48, Issue 6, Pages 911-913Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.12.045
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An efficient synthesis of the selective COX-2 inhibitor GW406381X is described via a novel intramolecular Mannich-type cyclisation to construct the pyrazolo-[1,5a]-pyridazine heterocyclic core. (c) 2006 Elsevier Ltd. All rights reserved.
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