Journal
SYNTHESIS-STUTTGART
Volume -, Issue 4, Pages 547-550Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-965878
Keywords
o-phenylenediamines; benzimidazoles; aryl aldehydes; hydrogen peroxide
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A simple and efficient procedure for the synthesis of substituted benzimidazoles through a one-pot condensation of o-phenylenediamines with aryl aldehydes in the presence of H2O(2)/HCl system in acetonitrile at room temperature is described. Short reaction time, large-scale synthesis, easy and quick isolation of the products, and excellent yields are the main advantages of this procedure.
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