Journal
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
Volume 45, Issue 4, Pages 688-698Publisher
WILEY
DOI: 10.1002/pola.21741
Keywords
atom transfer radical polymerization (ATRP); diblock copolymers; nanoparticles; poly(D,L-lactide) (PLA); poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)
Categories
Ask authors/readers for more resources
A poly(D,L-lactide)-bromine macroinitiator was synthesized for use in the preparation of a novel biocompatible polymer. This amphiphilic diblock copolymer consisted of biodegradable poly(D,L-lactide) and 2-methacryloyloxyethyl phosphorylcholine and was formed by atom transfer radical polymerization. Polymeric nanoparticles were prepared by a dialysis process in a select solvent. The shape and structure of the polymeric nanoparticles were determined by H-1 NMR, atomic force microscopy, and xi-potential measurements. The results of cytotoxicity tests showed the good cytocompatibility of the lipid-like diblock copolymer poly(2-methacryloyloxyethyl phosphorylcholine)block-poly(D,L-lactide). (c) 2006 Wiley Periodicals, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available