Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 72, Issue 4, Pages 1510-1513Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo062194s
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An efficient copper-catalyzed double alkenylation of amides with (1Z,3Z)-1,4-diiodo-1,3-dienes is reported for the first time. The reactions proceed to afford di- or trisubstituted N-acylpyrroles in good to excellent yields using CuI as the catalyst, Cs2CO3 as the base, and rac-trans-N,N'-dimethylcyclohexane-1,2-diamine as the ligand.
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