Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 72, Issue 4, Pages 1492-1494Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo061935m
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- NIGMS NIH HHS [GM 42056, R01 GM042056, R37 GM042056, R01 GM060287-01] Funding Source: Medline
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Opening of representative epoxides with 1,2-amino alcohols delivered the amino diols. The product amino diols were then oxidized under Swern conditions. The amino diketones so prepared were not isolated, but were condensed directly with hydroxylamine to give the substituted pyrazines.
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