4.4 Article

A concise synthesis of Tamiflu: third generation route via the Diels-Alder reaction and the Curtius rearrangement

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 8, Pages 1403-1406

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.12.093

Keywords

Tamiflu; Diels-Alder reaction; Curtius rearrangement

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Our third generation synthesis of Tamiflu was achieved in 12 steps from commercially available starting materials, using the Diels-Alder reaction and Curtius rearrangement as key steps. (c) 2006 Elsevier Ltd. All rights reserved.

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