Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 7, Pages 1978-1986Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja0651005
Keywords
-
Categories
Ask authors/readers for more resources
Optically active aluminum(salalen) complex 2 was newly synthesized in a modular synthetic manner, and it was found to serve as an efficient catalyst for hydrophosphonylation of aldehydes and aldimines, giving the corresponding alpha-hydroxy and alpha-amino phosphonates with high enantioselectivity, respectively. The scope of the hydrophosphonylation was wide, and both aliphatic and aromatic aldehydes and aldimines were successfully used as substrates for the reaction. The potent catalysis of the complex is attributed to its unique structure: it adopts a distorted trigonal bipyramidal configuration which allows the salalen ligand to take a cis-beta-like structure wherein the chiral amino group is located close to the metal center.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available