4.8 Article

Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain

Related references

Note: Only part of the references are listed.
Review Neurosciences

Multiple Functions of Endocannabinoid Signaling in the Brain

Istvan Katona et al.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 35 (2012)

Article Chemistry, Medicinal

Assay and inhibition of diacylglycerol lipase activity

Meghan Johnston et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Review Biochemistry & Molecular Biology

How Chemoproteomics Can Enable Drug Discovery and Development

Raymond E. Moellering et al.

CHEMISTRY & BIOLOGY (2012)

Article Biochemistry & Molecular Biology

DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

Ku-Lung Hsu et al.

NATURE CHEMICAL BIOLOGY (2012)

Review Biology

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

Melina Reisenberg et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)

Article Chemistry, Multidisciplinary

Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design

Christian Hedberg et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Chemistry, Multidisciplinary

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

Marion Rusch et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Biochemistry & Molecular Biology

Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α

Donna L. Pedicord et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Review Chemistry, Multidisciplinary

The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease

Jonathan Z. Long et al.

CHEMICAL REVIEWS (2011)

Article Neurosciences

Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight

Vincenzo Di Marzo

NATURE NEUROSCIENCE (2011)

Article Multidisciplinary Sciences

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

Daniel K. Nomura et al.

SCIENCE (2011)

Article Chemistry, Multidisciplinary

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat - An FDA-Approved Drug with Anti-Tumor Activities

Peng-Yu Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Biochemistry & Molecular Biology

Small-molecule inhibition of APT1 affects Ras localization and signaling

Frank J. Dekker et al.

NATURE CHEMICAL BIOLOGY (2010)

Article Chemistry, Multidisciplinary

beta-lactones as privileged structures for the active-site labeling of versatile bacterial

Thomas Boettcher et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Article Chemistry, Medicinal

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling

Heather S. Hoover et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Article Chemistry, Medicinal

Tetrahydrolipstatin Analogues as Modulators of Endocannabinoid 2-Arachidonoylglycerol Metabolism

Giorgio Ortar et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

beta-Lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana

Zheming Wang et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat

Charles W. Pemble et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Development of the first potent and specific inhibitors of endocannabinoid biosynthesis

T Bisogno et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)

Article Pharmacology & Pharmacy

Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity

AH Lichtman et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Biotechnology & Applied Microbiology

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

D Leung et al.

NATURE BIOTECHNOLOGY (2003)

Article Chemistry, Medicinal

α-Keto heterocycle inhibitors of fatty acid amide hydrolase:: Carbonyl group modification and α-substitution

DL Boger et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)

Article Multidisciplinary Sciences

Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide

DL Boger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)