Journal
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Volume 16, Issue 2, Pages 95-98Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.seizure.2006.10.007
Keywords
antiepileptic drug discontinuation; epilepsy surgery; temporal lobe epilepsy; temporal lobectomy; seizure freedom; seizure recurrence
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Data are limited on seizure recurrence after antiepileptic drug (AED) discontinuation in operated seizure-free patients. We reviewed seizure outcome in patients who came off AEDs after being seizure-free for 2 years following temporal lobe surgery in our center. Thirty-nine (68%) of 57 patients who discontinued AED therapy remained seizure-free. They had a younger age at surgery than the group with seizure recurrence (p = 0.01). Earlier surgery may be a favorable predictor for seizure freedom after AED discontinuation. (C) 2006 British Epilepsy Association. Published by Elsevier Ltd. AR rights reserved.
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