Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 52, Issue 18, Pages 4734-4743Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201210276
Keywords
arylation; catalysis; diazonium salts; radicals; visible light
Categories
Funding
- German Science Foundation (DFG) [GRK 1626]
Ask authors/readers for more resources
The use of diazonium salts for aryl radical generation and CH arylation processes has been known since 1896 when Pschorr first used the reaction for intramolecular cyclizations. Meerwein developed it further in the early 1900s into a general arylation method. However, this reaction could not compete with the transition-metal-mediated formation of C(sp2)C(sp2) bonds. The replacement of the copper catalyst with iron and titanium compounds improved the situation, but the use of photocatalysis to induce the one-electron reduction and activation of the diazonium salts is even more advantageous. The first photocatalyzed Pschorr cyclization was published in 1984, and just last year a series of papers described applications of photocatalytic Meerwein arylations leading to arylalkene coupling products. In this Minireview we summarize the origins of this reaction and its scope and applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available