☆ 4.8 Article

A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

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Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 52, Issue 47, Pages 12341-12345

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201307661

Keywords

nucleic acid analogues; RNA polymerase II; sugar integrity; synthetic biology; transcriptional fidelity

Categories

Chemistry, Multidisciplinary

Funding

  1. NIH (Sidney Kimmel Foundation for Cancer Research) [GM102362]
  2. Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD
  3. UCSD [T32 GM007752]

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