Journal
PITUITARY
Volume 10, Issue 1, Pages 81-86Publisher
SPRINGER
DOI: 10.1007/s11102-007-0014-1
Keywords
prolactinoma; temozolomide; dopamine agonist resistance
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Prolactinomas are common tumors of the anterior pituitary gland. While conventional therapies, including dopamine agonists, transsphenoidal surgery and radiotherapy, are usually effective in controlling tumor growth, some patients develop treatment-resistant tumors. In this report, we describe a patient with an invasive prolactinoma resistant to conventional therapy that responded to the administration of the alkylating agent, temozolomide.
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