Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 22, Issue 3, Pages 385-393Publisher
WILEY
DOI: 10.1359/JBMR.061116
Keywords
low-density lipoprotein receptor-related protein 5; single nucleotide polymorphisms; association; BMD; osteoporosis
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Funding
- NIAMS NIH HHS [K01 AR02170-01, R01 AR45349-01, R01 AR050496] Funding Source: Medline
- NIGMS NIH HHS [R01 GM60402-01A1] Funding Source: Medline
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In this study, the associations of novel LRP5 variants with BMD variation were detected and some replicated in the two ethnic groups of Chinese and white origins, respectively. These data support the concept that LRP5 variation can contribute to minor and major variation in bone structure.
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