Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 51, Issue 3, Pages 1105-1106Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01310-06
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The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 mu g/ml. The MIC,, and MIC,0 were 0.125 and 0.25 mu g/ml, respectively. These indicate that cloxyquin exhibited good antituberculosis activity, even for multidrug-resistant isolates.
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