Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 51, Issue 46, Pages 11426-11437Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201204687
Keywords
aryl fluorides; fluorine-18; heterocycles; positron emission tomography; radiochemistry
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Funding
- EPSRC
- CRUK
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Molecular imaging has witnessed an upsurge in growth, with positron emission tomography leading the way. This trend has encouraged numerous synthetic chemists to enter the field of 18F-radiochemistry and provide generic solutions to address the well-recognized challenges of late-stage fluorination. This Minireview focuses on recent developments in the 18F-labeling of aromatic substrates.
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