4.8 Article

Discovery of Macrocyclic Peptides Armed with a Mechanism-Based Warhead: Isoform-Selective Inhibition of Human Deacetylase SIRT2

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 51, Issue 14, Pages 3423-3427

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201108118

Keywords

FIT system; inhibitors; macrocyclic peptides; peptides; RaPID system

Funding

  1. Japan Society for Promotion of Science (JSPS)
  2. Specially Promoted Research [21000005]
  3. Industrial Science and Technology Program in the New Energy and Industrial Technology Development Organization (NEDO)
  4. [21-9079]

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