Journal
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Volume 292, Issue 3, Pages G706-G710Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/ajpgi.00347.2006
Keywords
Toll-like receptor 5; adaptive immunity; epithelial cell
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Recent observations suggest that bacterial flagellin may be a target of the seemingly aberrant innate and adaptive immune responses that are associated with Crohn's disease. This article discusses the evidence that supports a role for flagellin in Crohn's disease and considers the potential roles of these responses in the pathophysiology of this disorder.
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