4.8 Article

Drugs by Numbers: Reaction-Driven De Novo Design of Potent and Selective Anticancer Leads

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 52, Issue 17, Pages 4676-4681

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201206897

Keywords

drug design; enzyme inhibitors; fragment-based design; Polo-like kinase; virtual synthesis

Funding

  1. Deutsche Krebshilfe [108651]
  2. Wilhelm-Sander-Stiftung [2009.024.1]
  3. Messer-Stiftung
  4. Swiss National Science Foundation [205321-134783]
  5. Deutsche Forschungsgemeinschaft [FOR1406TP4]

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