Journal
ADDICTIVE BEHAVIORS
Volume 32, Issue 3, Pages 634-639Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.addbeh.2006.06.001
Keywords
posttraumatic stress disorder; alcohol; cocaine; dependence; relapse
Categories
Funding
- NIAAA NIH HHS [P50 AA 10751] Funding Source: Medline
- NIAMS NIH HHS [P50 AR 049551] Funding Source: Medline
- NIDA NIH HHS [K24 DA 00435, F31 DA006077] Funding Source: Medline
- PHS HHS [M01 RRO 1070] Funding Source: Medline
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The present study compared high-risk triggers and substance use situations among 72 (34 men, 38 women) individuals with alcohol (AD) or cocaine dependence (CD), with or without comorbid PTSD. Consistent with the self-medication hypothesis, individuals with PTSD reported significantly greater use of substances in response to negative situations, such as unpleasant emotions and physical discomfort, as compared to individuals without PTSD. CD individuals were significantly more likely than AD individuals to report using in temptation situations, regardless of PTSD status. Also, CD individuals with PTSD reported greater use of cocaine during pleasant times with others, as compared to those without PTSD. The findings highlight the importance of addressing individual-specific high-risk situations in relapse prevention. (c) 2006 Elsevier Ltd. All rights reserved.
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