Journal
MOLECULES
Volume 12, Issue 3, Pages 328-344Publisher
MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL
DOI: 10.3390/12030328
Keywords
Saussurea lappa; acylated flavone glycosides; scutellarein; kaempferol; antifungal acitivity
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The isolation of four novel acylated flavonoid glycosides from the roots of Saussurea lappa and their identification using a combination of ID and 2D NMR and mass spectrometry is described. The in vitro antifungal and antibacterial activities of the isolated compounds and their mixture were tested on nine fungal and four bacterial strains, using the microdilution method. The compounds and mixture showed moderate to high antifungal activity against most of the fungi tested, compared to a miconazole standard, while only one compound and the mixture showed antibacterial activity against all strains tested.
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