4.8 Review

Optochemical Genetics

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Tuning Photochromic Ion Channel Blockers

Alexandre Mourot et al.

ACS CHEMICAL NEUROSCIENCE (2011)

Review Chemistry, Multidisciplinary

Sweet and Umami Taste: Natural Products, Their Chemosensory Targets, and Beyond

Maik Behrens et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Chemistry, Multidisciplinary

Fluorescence Imaging of Azobenzene Photoswitching In Vivo

Andrew A. Beharry et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Neurosciences

Optogenetic photochemical control of designer K+ channels in mammalian neurons

Doris L. Fortin et al.

JOURNAL OF NEUROPHYSIOLOGY (2011)

Article Biotechnology & Applied Microbiology

LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness

Natalia Caporale et al.

MOLECULAR THERAPY (2011)

Article Multidisciplinary Sciences

The crystal structure of a voltage-gated sodium channel

Jian Payandeh et al.

NATURE (2011)

Article Multidisciplinary Sciences

Structure and function of an irreversible agonist-β2 adrenoceptor complex

Daniel M. Rosenbaum et al.

NATURE (2011)

Article Biochemical Research Methods

From cudgel to scalpel: toward precise neural control with optogenetics

Simon Peron et al.

NATURE METHODS (2011)

Article Biochemical Research Methods

Optogenetics

Karl Deisseroth

NATURE METHODS (2011)

Article Multidisciplinary Sciences

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

Andre Berndt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Chemical and Genetic Engineering of Selective Ion Channel-Ligand Interactions

Christopher J. Magnus et al.

SCIENCE (2011)

Article Multidisciplinary Sciences

Structure of an Agonist-Bound Human A2A Adenosine Receptor

Fei Xu et al.

SCIENCE (2011)

Article Multidisciplinary Sciences

A modern ionotropic glutamate receptor with a K+ selectivity signature sequence

H. Janovjak et al.

NATURE COMMUNICATIONS (2011)

Article Chemistry, Multidisciplinary

Light-Induced Control of Protein Trans location by the SecYEG Complex

Francesco Bonardi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Review Biochemistry & Molecular Biology

The epithelial sodium channel and the control of sodium balance

Laurent Schild

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)

Review Biochemistry & Molecular Biology

Pharmacology of ionotropic glutamate receptors: A structural perspective

Philipp Stawski et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

Viviana Gradinaru et al.

Article Multidisciplinary Sciences

Structural mechanism of C-type inactivation in K+ channels

Luis G. Cuello et al.

NATURE (2010)

Article Neurosciences

Ultrafast optogenetic control

Lisa A. Gunaydin et al.

NATURE NEUROSCIENCE (2010)

Review Pharmacology & Pharmacy

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

Stephen F. Traynelis et al.

PHARMACOLOGICAL REVIEWS (2010)

Article Multidisciplinary Sciences

Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

Xiaorui Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

Ellen Y. T. Chien et al.

SCIENCE (2010)

Article Multidisciplinary Sciences

Optogenetic Control of Cardiac Function

Aristides B. Arrenberg et al.

SCIENCE (2010)

Article Chemistry, Multidisciplinary

Photochromic Blockers of Voltage-Gated Potassium Channels

Matthew R. Banghart et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Article Neurosciences

Advances in Light Microscopy for Neuroscience

Brian A. Wilt et al.

Annual Review of Neuroscience (2009)

Review Biochemistry & Molecular Biology

Cellular and Molecular Mechanisms of Pain

Allan I. Basbaum et al.

Review Neurosciences

New photochemical tools for controlling neuronal activity

Richard H. Kramer et al.

CURRENT OPINION IN NEUROBIOLOGY (2009)

Editorial Material Biochemistry & Molecular Biology

Proteins: how RNA polymerases work Editorial overview

Patrick Cramer et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)

Article Multidisciplinary Sciences

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

Ricarda J. C. Hilf et al.

NATURE (2009)

Article Multidisciplinary Sciences

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

Eric B. Gonzales et al.

NATURE (2009)

Article Multidisciplinary Sciences

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

Alexander I. Sobolevsky et al.

NATURE (2009)

Article Multidisciplinary Sciences

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

Toshimitsu Kawate et al.

NATURE (2009)

Article Multidisciplinary Sciences

Predicting new molecular targets for known drugs

Michael J. Keiser et al.

NATURE (2009)

Article Multidisciplinary Sciences

Optogenetic dissection of a behavioural module in the vertebrate spinal cord

Claire Wyart et al.

NATURE (2009)

Article Biochemical Research Methods

Microscopy and its focal switch

Stefan W. Hell

NATURE METHODS (2009)

Article Neurosciences

Bi-stable neural state switches

Andre Berndt et al.

NATURE NEUROSCIENCE (2009)

Review Biotechnology & Applied Microbiology

Voltage-gated potassium channels as therapeutic targets

Heike Wulff et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Review Cell Biology

Regulators of the cytoplasmic dynein motor

Julia R. Kardon et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR

Rika Numano et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Optical Deconstruction of Parkinsonian Neural Circuitry

Viviana Gradinaru et al.

SCIENCE (2009)

Review Chemistry, Organic

Azobenzenes-synthesis and carbohydrate applications

Florian Hamon et al.

TETRAHEDRON (2009)

Review Chemistry, Multidisciplinary

Photocontrol of neural activity:: Biophysical mechanisms and performance in vivo

Lucas Sjulson et al.

CHEMICAL REVIEWS (2008)

Review Chemistry, Multidisciplinary

Serotonin receptors

David E. Nichols et al.

CHEMICAL REVIEWS (2008)

Article Multidisciplinary Sciences

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

Ricarda J. C. Hilf et al.

NATURE (2008)

Article Biochemical Research Methods

Engineering GPCR signaling pathways with RASSLs

Bruce R. Conklin et al.

NATURE METHODS (2008)

Review Cell Biology

A structural understanding of the dynamic ribosome machine

Thomas A. Steitz

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Cell Biology

Heterotrimeric G protein activation by G-protein-coupled receptors

William M. Oldham et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Neurosciences

Imaging in vivo: watching the brain in action

Jason N. D. Kerr et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Article Multidisciplinary Sciences

α-Helix folding in the presence of structural constraints

Janne A. Ihalainen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Multidisciplinary Sciences

Optical switches for remote and noninvasive control of cell signaling

Pau Gorostiza et al.

SCIENCE (2008)

Article Chemistry, Multidisciplinary

All optical interface for parallel, remote, and spatiotemporal control of neuronal activity

Sheng Wang et al.

NANO LETTERS (2007)

Article Multidisciplinary Sciences

Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH

Jayasankar Jasti et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Crystal structure of a Kir3.1-prokaryotic Kir channel chimera

Motohiko Nishida et al.

EMBO JOURNAL (2007)

Review Neurosciences

Circuit-breakers: optical technologies for probing neural signals and systems

Feng Zhang et al.

NATURE REVIEWS NEUROSCIENCE (2007)

Review Biochemical Research Methods

Caged compounds: photorelease technology for control of cellular chemistry and physiology

Graham C. R. Ellis-Davies

NATURE METHODS (2007)

Article Chemistry, Multidisciplinary

Imaging cell surface glycans with bioorthogonal chemical reporters

Pamela V. Chang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Review Neurosciences

TRP channels in mechanosensation: direct or indirect activation?

Adam P. Christensen et al.

NATURE REVIEWS NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor

Pau Gorostiza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Neurosciences

The action potential in mammalian central neurons

Bruce P. Bean

NATURE REVIEWS NEUROSCIENCE (2007)

Review Neurosciences

NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

C. Geoffrey Lau et al.

NATURE REVIEWS NEUROSCIENCE (2007)

Article Neurosciences

Remote control of neuronal activity with a light-gated glutamate receptor

Stephanie Szobota et al.

NEURON (2007)

Article Multidisciplinary Sciences

Multimodal fast optical interrogation of neural circuitry

Feng Zhang et al.

NATURE (2007)

Article Multidisciplinary Sciences

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

Blaine N. Armbruster et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors

Takanori Muto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Chemistry, Multidisciplinary

Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors

Matthew Volgraf et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Review Pharmacology & Pharmacy

Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors

Hans Brauner-Osborne et al.

CURRENT DRUG TARGETS (2007)

Article Biochemistry & Molecular Biology

Engineering light-gated ion channels

Matthew R. Banghart et al.

BIOCHEMISTRY (2006)

Article Neurosciences

Light-induced depolarization of neurons using a modified Shaker K+ channel and a molecular photoswitch

James J. Chambers et al.

JOURNAL OF NEUROPHYSIOLOGY (2006)

Article Neurosciences

Next-generation optical technologies for illuminating genetically targeted brain circuits

Karl Deisseroth et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Biochemistry & Molecular Biology

Structural determinants of natriuretic peptide receptor specificity and degeneracy

Xiao-lin He et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Multidisciplinary Sciences

Atomic structure of a Na+- and K+-conducting channel

N Shi et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Deciphering the structural framework of glycine receptor anchoring by gephyrin

EY Kim et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Allosteric control of an ionotropic glutamate receptor with an optical switch

M Volgraf et al.

NATURE CHEMICAL BIOLOGY (2006)

Article Neurosciences

Millisecond-timescale, genetically targeted optical control of neural activity

ES Boyden et al.

NATURE NEUROSCIENCE (2005)

Article Multidisciplinary Sciences

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

SB Long et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

A light-actuated nanovalve derived from a channel protein

A Koçer et al.

SCIENCE (2005)

Review Biochemistry & Molecular Biology

Chemistry in living systems

JA Prescher et al.

NATURE CHEMICAL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Structural basis of TEA blockade in a model potassium channel

MJ Lenaeus et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution

N Unwin

JOURNAL OF MOLECULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

MH Nanao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Biochemistry & Molecular Biology

Manipulating proteins with chemistry: a cross-section of chemical biology

ME Hahn et al.

TRENDS IN BIOCHEMICAL SCIENCES (2005)

Article Biochemistry & Molecular Biology

The retinal conformation and its environment in rhodopsin in light of a new 2.2 Å crystal structure

T Okada et al.

JOURNAL OF MOLECULAR BIOLOGY (2004)

Article Multidisciplinary Sciences

Chemical remodelling of cell surfaces in living animals

JA Prescher et al.

NATURE (2004)

Article Chemistry, Multidisciplinary

Lipid-mediated light activation of a mechanosensitive channel of large conductance

JHA Folgering et al.

LANGMUIR (2004)

Article Neurosciences

Light-activated ion channels for remote control of neuronal firing

M Banghart et al.

NATURE NEUROSCIENCE (2004)

Review Neurosciences

Receptor trafficking and synaptic plasticity

GL Collingridge et al.

NATURE REVIEWS NEUROSCIENCE (2004)

Article Pharmacology & Pharmacy

Activation mechanism of the heterodimeric GABAB receptor

JP Pin et al.

BIOCHEMICAL PHARMACOLOGY (2004)

Article Multidisciplinary Sciences

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

G Nagel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

The receptors for mammalian sweet and umami taste

GQ Zhao et al.

Review Biochemistry & Molecular Biology

Ionotropic glutamate receptor biology: Effect on synaptic connectivity and function in neurological disease

GN Barnes et al.

CURRENT MEDICINAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

X-ray structure of a voltage-dependent K+ channel

YX Jiang et al.

NATURE (2003)

Article Multidisciplinary Sciences

Photochemical gating of heterologous ion channels:: Remote control over genetically designated populations of neurons

BV Zemelman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

An unusual receptor tyrosine kinase of Schistosoma mansoni contains a Venus Flytrap module

J Vicogne et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2003)

Article Physiology

Kinetics of tethering quaternary ammonium compounds to K+ channels

RO Blaustein

JOURNAL OF GENERAL PHYSIOLOGY (2002)

Article Multidisciplinary Sciences

Crystal structure and mechanism of a calcium-gated potassium channel

YX Jiang et al.

NATURE (2002)

Review Neurosciences

Potassium channel structures

S Choe

NATURE REVIEWS NEUROSCIENCE (2002)

Review Neurosciences

Emerging structure of the nicotinic acetylcholine receptors

A Karlin

NATURE REVIEWS NEUROSCIENCE (2002)

Article Neurosciences

Selective photostimulation of genetically ChARGed neurons

BV Zemelman et al.

NEURON (2002)

Review Cell Biology

ATP synthase - A marvellous rotary engine of the cell

M Yoshida et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)

Review Biochemistry & Molecular Biology

Chemical genetic approaches for the elucidation of signaling pathways

PJ Alaimo et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2001)

Review Neurosciences

Molecular physiology of P2X receptors and ATP signalling at synapses

BS Khakh

NATURE REVIEWS NEUROSCIENCE (2001)

Review Genetics & Heredity

Chemical genetics: Ligand-based discovery of gene function

BR Stockwell

NATURE REVIEWS GENETICS (2000)

Review Multidisciplinary Sciences

RNA polymerase II elongation through chromatin

G Orphanides et al.

NATURE (2000)

Review Neurosciences

Neuronal nicotinic receptors in the human brain

D Paterson et al.

PROGRESS IN NEUROBIOLOGY (2000)