4.8 Article

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 50, Issue 34, Pages 7837-7841

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201102094

Keywords

amino acids; asymmetric synthesis; cycloaddition; phosphines; spiro compounds

Funding

  1. National University of Singapore
  2. Ministry of Education (MOE) of Singapore [R-143-000-362-112]

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