4.8 Article

The Use of Fluoride as a Leaving Group: SN2' Displacement of a C?F Bond on 3,3-Difluoropropenes with Organolithium Reagents To Give Direct Access to Monofluoroalkenes

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 50, Issue 47, Pages 11112-11116

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201105138

Keywords

monofluoroalkenes; nucleophilic substitution; organofluorine compounds; organolithium reagents; synthetic methods

Funding

  1. Canada Research Chair Program
  2. Natural Sciences and Engineering Research Council of Canada
  3. Canada Foundation for Innovation
  4. Fonds de recherche sur la nature et les technologies (FQRNT)
  5. Pfizer Global Research Development
  6. FQRNT Centre in Green Chemistry and Catalysis (CGCC)
  7. Universite Laval

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