Journal
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Volume 7, Issue 3, Pages 852-855Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2007.520
Keywords
electrospinning; water-insoluble treatment; chitosan nanofiber; coating chitosan-cast film; crab-tendon chitosan; nerve-regenerative guide tube
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Water-insoluble chitosan nanofiber sheets and tubes coated with chitosan-cast film were prepared by electrospinning. When as-spun chitosan nanofiber sheets and tubes were immersed in 28% ammonium aqueous solution, they became insoluble in water and showed nanofiber structures confirmed by SEM micrography. Mechanical properties of chitosan nanofiber sheets and tubes were improved by coating with chitosan-cast film, which gave them a compressive strength higher than that of crab-tendon chitosan, demonstrating that chitosan nanofiber tubes coated with chitosan-cast film are usable as nerve-regenerative guide tubes.
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