Journal
HEART RHYTHM
Volume 4, Issue 3, Pages S1-S6Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.hrthm.2006.12.018
Keywords
atrial fibrillation; incidence; prevalence; risk factors; genetic epidemiology
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The prevalence of atrial fibrillation (AF) increases with age. Recent population-based data indicate a trend of increasing incidence and prevalence of AF that is incompletely explained by an aging population. A recent population study estimated that the number of Americans afflicted by AF will increase from the current 2.3 million to more than 10 million by 2050. Novel risk factors-obesity and steep apnea-may partially account for the current AF epidemic. Ethnic differences in the epidemiology of AF have been suggested but not clearly elucidated by population-based studies. The heritability of AF in the general population is strongly supported by population-based data. Genetic epidemiological studies on AF can potentially yield important mechanistic insights that may ultimately lead to novel preventative and therapeutic strategies.
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