Journal
SCIENCE
Volume 315, Issue 5816, Pages 1243-1249Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1136281
Keywords
-
Categories
Ask authors/readers for more resources
The rostral migratory stream (RMS) is the main pathway by which newly born subventricular zone cells reach the olfactory bulb ( OB) in rodents. However, the RMS in the adult human brain has been elusive. We demonstrate the presence of a human RMS, which is unexpectedly organized around a lateral ventricular extension reaching the OB, and illustrate the neuroblasts in it. The RMS ensheathing the lateral olfactory ventricular extension, as seen by magnetic resonance imaging, cell-specific markers, and electron microscopy, contains progenitor cells with migratory characteristics and cells that incorporate 5-bromo-2'-deoxyuridine and become mature neurons in the OB.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available