Journal
VACCINE
Volume 25, Issue 12, Pages 2238-2243Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2006.12.010
Keywords
lumpy skin disease virus; neethling strain vaccine; semen
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Twelve serologically negative bulls were used, six were vaccinated with a modified live LSD vaccine and six unvaccinated. All were then experimentally infected with a virulent field strain of LSDV. No clinical abnormality was detected following vaccination, and mild clinical signs were seen in four vaccinated bulls following challenge. Virus was not found in semen of vaccinated bulls. Two of the unvaccinated bulls developed severe LSD and four showed mild symptoms, all excreted the virus in the semen following challenge. This study confirmed the ability of LSD vaccination to prevent the excretion of LSDV in semen of vaccinated bulls. (c) 2006 Elsevier Ltd. All rights reserved.
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