4.8 Article

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 50, Issue 7, Pages 1678-1682

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201005908

Keywords

asymmetric catalysis; asymmetric synthesis; homoenolates; Lewis acids; N-heterocyclic carbenes

Funding

  1. NIH (NIGMS) [RO1 GM73072]
  2. Amgen
  3. AstraZeneca
  4. GlaxoSmithKline
  5. GAANN (Graduate Assistance in Areas of Nation Need) fellowship
  6. FQRNT (Fonds Quebecois de la Recherche sur la Nature et les Technologies)
  7. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM073072] Funding Source: NIH RePORTER

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