Journal
SYNLETT
Volume -, Issue 5, Pages 806-808Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-970755
Keywords
N-Boc protection; environmentally benign; solvent-free; catalyst-free
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A practical and highly efficient method for the protection of amines to their corresponding N-Boc derivatives is reported. In the absence of any solvent and catalyst, the present strategy works well for a series of electron-deficient and electron-rich aromatic amines as well as some sterically hindered substrates.
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