4.4 Article

NbCl5-catalyzed one-pot Mannich-type reaction:: three component synthesis of β-amino carbonyl compounds

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 12, Pages 2071-2073

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.01.142

Keywords

NbCl5; Mannich-type reaction; beta-amino carbonyl compound; one-pot reaction

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Three-component Mannich-type reaction of acetophenone, aromatic aldehydes and aromatic amines was catalyzed by NbCl5 at ambient temperature to give various P-amino ketones in high yields, (c) 2007 Elsevier Ltd. All rights reserved.

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