☆ 4.8 Article

A Fragment-Based In Situ Combinatorial Approach To Identify High-Affinity Ligands for Unknown Binding Sites

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

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Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 49, Issue 33, Pages 5721-5725

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.200907254

Keywords

in situ click chemistry; fragment-based in situ combinatorial approach; drug discovery; glycoproteins; NMR spectroscopy

Categories

Chemistry, Multidisciplinary

Funding

  1. Volkswagen Foundation
  2. Swiss National Science Foundation
  3. German Federal Ministry for Education and Research (BMBF) [031632A]
  4. Tonjes-Vagt Foundation

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