4.8 Article

Design and Folding of [Glu(A4)(O(beta)Thr(B30))]Insulin (Ester Insulin): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 49, Issue 32, Pages 5489-5493

Publisher

WILEY-BLACKWELL
DOI: 10.1002/anie.201001151

Keywords

chemical ligation; chemical protein synthesis; esters; insulin; protein folding

Funding

  1. NIH [RO1 GM075993, DK040949, DK074176]
  2. American Diabetes Association [1-08-RA-218]
  3. JSPS
  4. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK074176, R01DK040949] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM075993] Funding Source: NIH RePORTER

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