4.8 Article

Generating patterns for sensing using a single receptor scaffold

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 12, Pages 3506-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja070229f

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Funding

  1. NIGMS NIH HHS [GM-65255] Funding Source: Medline

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A new strategy for generating patterns in sensing is described. Typically, pattern recognition is obtained by designing a variety of receptors that bind to analytes with varying binding affinities. In this paper, we outline a new strategy where differential responses can be obtained from one receptor, by simply varying the noncovalently bound fluorescent transducer.

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